Immune checkpoint inhibitors (ICIs) are increasingly used in the treatment of many tumor types, and durable responses can be observed in select populations.However, patients may exhibit significant immune-related adverse events (irAEs) that may lead to morbidity.There is limited information on whether the presence of specific germline mutations may
Soil moisture (SM) information can be routinely obtained from high-quality microwave retrievals at a global scale—such as datasets generated by the Soil Moisture Active Passive (SMAP) mission.In this article, using mutual information (MI) theory, we investigate the efficacy of the downscaled SMAP/Sentinel-1 L2 3-km EASE-Grid SM produc
Laundry All-in-One Abstract Background Breast cancer, the most diagnosed cancer, remains the second leading cause of cancer death in the United States, and excessive Progesterone (PRG) or Mifepristone (MIF) exposure may be at an increased risk for developing breast cancer.PRG exerts its cellular responses through signaling cascades involving classi
Alcohol (ethanol) is one of the most common addictive psychoactive substances in the world, and alcoholism may result in harmful effects on human health, especially on the nervous system.Flavonoids are regarded as the main active constituent in Epimedium, which has been used to cure some nervous system diseases such as amnesia for over 1000 years.H
Abstract The advent of x-ray free-electron lasers has enabled a range of new experimental investigations into the properties of matter driven to extreme conditions via intense Guide Rod Retainer x-ray-matter interactions.The femtosecond timescales of these interactions lead to the creation of transient high-energy-density plasmas, where both the el